Global RPH Renal Function Calculator (eGFR MDRD)

eGFR MDRD Formula:

\[ eGFR = 175 \times (Scr / 0.7)^{-0.203} \times (0.742 \text{ if female}) \times (1.212 \text{ if African American}) \times (age)^{-0.328} \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Ethnicity:

African American Other

eGFR (mL/min/1.73m²):

Definition: This calculator estimates glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease (MDRD) study equation.

Purpose: It helps healthcare professionals assess kidney function and stage chronic kidney disease (CKD).

The calculator uses the MDRD formula:

\[ eGFR = 175 \times (Scr / 0.7)^{-0.203} \times (0.742 \text{ if female}) \times (1.212 \text{ if African American}) \times (age)^{-0.328} \]

Where:

Explanation: The formula estimates kidney function based on creatinine levels adjusted for age, gender, and ethnicity.

Details: eGFR is crucial for detecting kidney disease, monitoring progression, and guiding medication dosing.

Tips: Enter serum creatinine (mg/dL), age (18+ years), select gender and ethnicity. All values must be valid.

Q1: What's the normal eGFR range?
A: Normal is ≥90 mL/min/1.73m². Values below 60 for 3+ months indicate CKD.

Q2: Why different factors for gender/ethnicity?
A: Muscle mass and creatinine production vary by gender and ethnicity.

Q3: When is MDRD not appropriate?
A: Not for acute kidney injury, children, pregnant women, or extremes of body size.

Q4: How accurate is MDRD?
A: Reasonably accurate for GFR <60 but less precise at normal ranges.

Q5: What's the difference between MDRD and CKD-EPI?
A: CKD-EPI is more accurate at higher GFRs and is now preferred.