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Global RPH Calculator for CrCl using Cockcroft-Gault

Cockcroft-Gault Formula:

\[ CrCl = \frac{(140 - age) \times weight \times (0.85\ if\ female)}{72 \times Scr} \]

years
kg
mg/dL

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1. What is the Cockcroft-Gault Formula?

Definition: The Cockcroft-Gault formula estimates creatinine clearance (CrCl), which correlates with the glomerular filtration rate (GFR).

Purpose: It helps healthcare professionals assess kidney function for medication dosing and renal impairment evaluation.

2. How Does the Calculator Work?

The calculator uses the Cockcroft-Gault formula:

\[ CrCl = \frac{(140 - age) \times weight \times (0.85\ if\ female)}{72 \times Scr} \]

Where:

Explanation: The formula estimates the rate at which creatinine is cleared from the blood by the kidneys.

3. Importance of CrCl Calculation

Details: Accurate CrCl estimation is crucial for proper dosing of renally excreted medications and assessing kidney function.

4. Using the Calculator

Tips: Enter the patient's age in years, weight in kg, serum creatinine in mg/dL, and select gender. All values must be > 0.

5. Frequently Asked Questions (FAQ)

Q1: When should I use this calculator?
A: Use when dosing medications that require renal adjustment or assessing kidney function in adults.

Q2: What are the limitations of this formula?
A: Less accurate in very obese, very underweight, or elderly patients. Not validated for children.

Q3: Why is there a gender adjustment?
A: Females typically have lower muscle mass (source of creatinine) than males at the same weight.

Q4: What's a normal CrCl range?
A: Normal is about 90-120 mL/min. Below 60 indicates renal impairment, below 30 severe impairment.

Q5: Should I use actual or ideal body weight?
A: For obese patients (BMI >30), consider using ideal body weight or adjusted body weight.

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