Cockcroft-Gault Formula:
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Definition: The Cockcroft-Gault formula estimates creatinine clearance (CrCl), which correlates with the glomerular filtration rate (GFR).
Purpose: It helps healthcare professionals assess kidney function for medication dosing and renal impairment evaluation.
The calculator uses the Cockcroft-Gault formula:
Where:
Explanation: The formula estimates the rate at which creatinine is cleared from the blood by the kidneys.
Details: Accurate CrCl estimation is crucial for proper dosing of renally excreted medications and assessing kidney function.
Tips: Enter the patient's age in years, weight in kg, serum creatinine in mg/dL, and select gender. All values must be > 0.
Q1: When should I use this calculator?
A: Use when dosing medications that require renal adjustment or assessing kidney function in adults.
Q2: What are the limitations of this formula?
A: Less accurate in very obese, very underweight, or elderly patients. Not validated for children.
Q3: Why is there a gender adjustment?
A: Females typically have lower muscle mass (source of creatinine) than males at the same weight.
Q4: What's a normal CrCl range?
A: Normal is about 90-120 mL/min. Below 60 indicates renal impairment, below 30 severe impairment.
Q5: Should I use actual or ideal body weight?
A: For obese patients (BMI >30), consider using ideal body weight or adjusted body weight.